Webb11 juni 2009 · The nitrophorins (NPs) are a group of NO-carrying ferriheme proteins found in the saliva of the blood-sucking insect Rhodnius prolixus. At least five NPs, i.e., NP1, NP2, NP3, NP4, and NP7, are expressed in varying amounts during the six developmental stages of the insect’s life cycle [ 1, 2 ]. Webb18 juli 2006 · Sequence domains: Nitrophorin Structure domains: Lipocalin. Ligands and Environments 1 bound ligand: 1 x HEM. No modified residues. Experiments and Validation Details. X-ray source: APS BEAMLINE 14-BM-C. Spacegroup: P4 1 2 1 2. Unit cell: a: 34.526Å b: 34.526Å c: 255.76Å ...
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WebbKnipp M, Yang F, Berry RE, Zhang H, Shokhirev MN, et al. (2007) Spectroscopic and functional characterization of nitrophorin 7 from the blood-feeding insect Rhodnius prolixus reveals an important role of its isoform-specific N-terminus for proper protein function. Biochemistry 46: 13254-13268. WebbTo this end, we investigated whether double-stranded RNA (dsRNA) can inhibit gene expression of R. prolixus salivary nitrophorin 2 (NP2) and what impact this might … left shift operator in binary
The Crystal Structure of Nitrophorin 2 - Journal of Biological Che…
Webb9 juni 2003 · Crystal structure of nitrophorin 2 L122V/L132V mutant complex with imidazole. PDB DOI: 10.2210/pdb1PM1/pdb; Classification: BLOOD CLOTTING … Webb15 maj 2002 · Saliva of the hard tick and Lyme disease vector, Ixodes scapularis, has a repertoire of compounds that counteract host defenses. Following sequencing of an I scapularis salivary gland complementary DNA (cDNA) library, a clone with sequence homology to tissue factor pathway inhibitor (TFPI) was identified. This cDNA codes for … Webb26 mars 2012 · The NIS data for nitrophorin 2 (NP2) shown in Figure 1a have been calculated by quantum mechanical (QM) density functional theory (DFT) coupled with molecular mechanics (MM) methods ( Figure 1b and 1c ). The simulations identify iron-NO binding modes ( Figure 2 ), but also functionally relevant low-energy modes ( Figure 3 ). left shift operator c++