Web27 apr 2024 · Some studies have suggested heterogeneous nuclear ribonucleoprotein A2/B1 (HNRNPA2B1) to be a promoter in cancer development. Nonetheless, no detailed pan-cancer investigation has … Web9 apr 2024 · 周国瑛团队的免疫荧光研究发现,hnRNPA2B1主要位于细胞核中,在未感染的细胞中,但在病毒感染的12-18小时,大量的hnRNPA2B1从细胞核涌出,快速转运到细胞质的高尔基体附近,研究预示,hnRNPA2B1正是在上述第二种病毒释放的途径中发挥了作用,而它也利用同样机制促进了外秘体的胞外释放。
剪接因子异质核糖核蛋白A2B1在癌细胞和衰老细胞中的相反表达趋 …
Web18 lug 2024 · DNA viruses typically eject genomic DNA into the nuclei of host cells after entry. It is unclear, however, how nuclear pathogen–derived DNA triggers innate immune responses. We report that heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) recognizes pathogenic DNA and amplifies interferon-α/β (IFN-α/β) production. Web19 gen 2016 · Human hnRNP A2/B1 is an RNA-binding protein that plays important roles in many biological processes, including maturation, transport, and metabolism of mRNA, … otl form
HNRNPA2B1 Gene - GeneCards ROA2 Protein
WebKnocking down HNRNPA2B1 in cancer cells leads to a series of senescence-associated phenotypes. In line with its function as a splicing factor, HNRNPA2B1 downregulation … Web14813-1-AP targets HNRNPA2B1 in WB, RIP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Web3 ott 2024 · hnRNPA2B1: Fueling Antiviral Immunity from the Nucleus. In a recently published article in Science, Cao and colleagues (. Wang et al., 2024. ) identify hnRNPA2B1 as a new DNA-binding protein that initiates and amplifies antiviral immunity, unveiling a new facet of DNA recognition in the nucleus. otl freight