High aconitine injection
Web1 de nov. de 2024 · Six compounds are extracted from aconitine hydrolysate according to high-resolution mass spectrometry data, retention time and multistage fragment ions (Table 2 and Fig. 3). Compared with the literature and standard, m / z of 646.32 is aconitine whose MS n fragmentation ions is shown in Fig. 3 A. m / z of 630.33 is inaconitine, which is the … Web27 de fev. de 2024 · Purpose Monkshood is a wild growing plant which contains the very toxic alkaloid aconitine, and is often used in traditional Chinese medicine. In this case report, we describe a fatal accident after the unintentional consumption of an aconite extract. Method By applying high-performance liquid chromatography–tandem mass …
High aconitine injection
Did you know?
WebAconitine is a neurotoxin which activates tetrodotoxin-sensitive Na + channels, inducing presynaptic depolarization and blocking the release of neurotransmitters. Aconitine also … WebAconitine is among the most toxic alkaloidsknown. Toxic doses are close to therapeuticdoses, and in humans as little as 2 mgmay cause death (Ferry and Vigneau 1983).An oral lethal dose of 28 mg/kg has alsobeen recorded (NIOSH 1986). The toxicsymptoms at low doses may be excitement,drowsiness, and hypermotility.
WebDownload : Download high-res image (757KB) Download : Download full-size image; ... 60 min after intraperitoneal injection of aconitine (0.0500 mg/kg, n = 6 mice/group). (F) Time of licking feet within 30 min after the intraplantar injection of menthol (100 mM, 10 µL) 60 min after intraperitoneal injection of aconitine (0.0500 mg ... Web27 de out. de 2024 · To further study the role of NLRP3 inflammasomes in aconitine‐induced cardiomyocyte damage, the NLRP3 inhibitor MCC950 was added to the aconitine‐treated H9c2 cells.38, 39, 40 The cleavage of pro‐Caspase‐1 and pro‐IL‐1β and expression of NLRP3 after aconitine incubation were severely suppressed by MCC950 …
WebMethods: The in vivo experimental groups were as follows:control group, low-dose, middle-dose and high-dose group. Arrhythmia in rats was induced by aconitine injection, and … Web1 de dez. de 2010 · Aconitine and hypaconitine were linear in the concentration ranges of 17.2-275 microg x L(-1) and 34. 4-550 microg x L(-1), respectively. The average recovery was more than 93.9% with the RSD of 3.8%.
WebHome - PLOS
Web1 de dez. de 2010 · To set up a capillary electrophoresis method with field-amplified sample injection for the determination f aconitine and hypaconitine in Gucixiaotong Ye. Method An uncoated fused-silica capillary column (50 microm x 50 cm, effective length 42 cm) was used as the separation channel. trust me i am from the governmenthttp://blog.arthritis.org/osteoarthritis/hyaluronic-acid-injections-knee-osteoarthritis/ trust me i know what i\u0027m doingWeb20 de jun. de 2016 · Using activity-guided fractionation, we isolated neoline from PA extract as the active ingredient. Neoline significantly alleviated L-OHP-induced reduction of … philips air fryer recipes chickenWeb1 de nov. de 2024 · At the injection amount of 4 mg/kg, aconitine doubled the survival time of the mice compared with the mice in the solvent control (Figure 4B). To examine the histology of the tumors and the proliferation of tumor cells, tumor tissue sections were stained with hematoxylin and eosin ( Figure 4C , upper panel) and Ki-67 ( Figure 4C , … trust me instrumental richard smallwoodWebMethods: This study consisted of 3 experiments that were designed to test the effects of injection of 30 μg/kg of aconitine at acupoints on the PM (Test 1), at non-acupoint sites … trust me in this in the bibleWebIf someone receives too much acetaminophen injection, get medical help immediately, even if the person does not have any symptoms. Symptoms of overdose may include the … trust me in this placeWeb29 de dez. de 2012 · Objective To investigate the ability of the pericardium meridian (PM) to mitigate or enhance the cardiotoxic effects of aconitine injected at specific acupoint and non-acupoint sites in rabbits. Methods This study consisted of 3 experiments that were designed to test the effects of injection of 30 μg/kg of aconitine at acupoints on the PM … philips air fryer recipes french fries