Hepatocyte nuclear factor 4α

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August undefined, 2024

WebThe expression level of DD4 mRNA significantly correlated with that of HNF-1α, HNF-4α or HNF-4γ. These results suggest that the expression level of DD4 mRNA is cooperatively … WebMultiple nuclear receptors, including hepatocyte nuclear factor 4α (HNF4α), retinoid X receptor α (RXRα) plus peroxisome proliferator-activated receptor α (PPARα), RXRα …

Hepatocyte nuclear factors - Wikipedia

WebHNF-4α is a highly conserved transcription factor that has the potential capacity to transactivate a vast number of genes, including CYP7 which codes for cholesterol 7α … Web21 mrt. 2024 · HNF4A (Hepatocyte Nuclear Factor 4 Alpha) is a Protein Coding gene. Diseases associated with HNF4A include Fanconi Renotubular Syndrome 4 With … dallas apartment rental prices

Hepatocyte nuclear factors - Wikipedia

WebY. Xu et al., Hepatocyte nuclear factor 4α prevents the steatosis-to-NASH progression by regulating p53 and bile acid signaling (in mice). Hepatology 73, 2251–2265 (2024). ... WebHepatocyte nuclear factor 4a orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver Michele A. Battle*, Genevieve Konopka*, … WebHepatocyte nuclear factor 4α (HNF4α), an important transcriptional factor of the nuclear hormone receptor family, is essential for normal liver architecture, morphological and … marietta spice mill

Regulatory Mechanisms Controlling Human Hepatocyte Nuclear …

Limited effects of bile acids and small heterodimer partner on ...

Web15 mrt. 2024 · Down-regulation of hepatocyte nuclear factor-4α expression and defective zonation in livers have not been recognized so far as features of the liver disease caused … HNF-4α is a nuclear transcription factor that binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene plays a role in development of the liver, kidney, and intestines. Alternative splicing of this gene results in multiple transcript variants. marietta special needs preschoolWeb1 mrt. 2009 · Hepatocyte nuclear factor-4α (HNF4α) is a nuclear receptor superfamily which plays an important role in early hepatocytes development [2]. HNF4α is a master … dallas aquarium discount code

"WebA combination of adenoviral transfections for CCAAT/enhancer-binding protein β (C/EBPβ), hepatocyte nuclear factor 4α (HNF4α), and constitutive androstane receptor (CAR) … " - Hepatocyte nuclear factor 4α

Hepatocyte nuclear factor 4α

WebWe have recently established F9 cells expressing doxycycline-inducible hepatocyte nuclear factor (HNF)-4α and shown that HNF-4α triggers the gene expression of tight … WebChromosomal abnormalities, epigenetic alterations, and environmental factors may contribute to the pathogenesis of CRC. ... PTB1/PKM1/PKM2 feedback cascade, 16 …

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Web29 jul. 2016 · Hepatocyte Nuclear Factor 4α (HNF4α) Is a Transcription Factor of Vertebrate Fatty Acyl Desaturase Gene as Identified in Marine Teleost Siganus … WebHepatocyte nuclear factors (HNFs) are a family of transcription factors that regulate liver-specific gene expression and hepatocyte differentiation [11–14].Some HNFs (HNF1α, …

WebHepatocyte nuclear factor (HNF)-4α is a liver-enriched transcription factor that regulates numerous liver-expressed genes including several sex-specific cytochrome P450 genes. … Web1 mrt. 2011 · CYP3A41 is a female-specific cytochrome P450 in mouse liver. A putative hepatocyte nuclear factor 4α (HNF4α)-binding site was found at −99/−87 in the …

Web29 sep. 2010 · Hepatocyte nuclear factor 4α (HNF4α) is a transcription factor that plays a key role in hepatocyte differentiation and the maintenance of hepatic function, but its … Web25 mei 2024 · Background Hepatocyte nuclear factor 4α (HNF4α) and glucocorticoid receptor (GR), master regulators of liver metabolism, are down-regulated in fatty liver …

Web6 okt. 2016 · Immunofluorescence microscopy of human hepatocyte spheroids after 3-4 weeks of long-term culture confirmed the presence of …

Web10 apr. 2024 · HNF-4α: Hepatocyte nuclear factor 4α (HNF-4α) is a highly conserved member of the nuclear hormone receptor super-family (NR2A1), which is normally … marietta spine and rehabWeb23 okt. 2024 · Hepatocyte nuclear factor 4α (HNF4α) is highly enriched in the liver, but its role in the progression of nonalcoholic liver steatosis (NAFL) to NASH has not been … marietta spine centerWeb5 sep. 2024 · Hepatocyte Nuclear Factor 4 Alpha (HNF4α) is a master transcription factor mainly expressed in the liver, kidney, intestine and endocrine pancreas. It regulates … marietta spinediWebHNF4-α is the most abundant hepatic DNA-binding protein, influencing the expression of approximately 40% of actively transcribed hepatic genes, including HNF1A and other … dallas aquarium shoebill storkWeb22 okt. 2024 · Hepatocyte nuclear factor 4 alpha (HNF4α) is a key master transcriptional factor for hepatic fat and bile acid metabolic pathways. We aimed to investigate the role … dallas aquarium student discountWeb10 aug. 2009 · Background and aims Hepatocyte nuclear factor 4α (HNF4α) is a central transcriptional regulator of hepatocyte differentiation and function. The aim of this study … dallas aquarium otterWebDecreased expression of hepatocyte nuclear factor 4α (Hnf4α)/microRNA-122 (miR-122) axis in hepatitis B virus-associated hepatocellular carcinoma enhances potential … dallas aquarium special offers