Dimethylindole red
WebJul 5, 2024 · Abstract. An RNA aptamer selected for binding to the fluorogenic cyanine dye, dimethylindole red (DIR), also binds and activates another cyanine, oxazole thiazole blue (OTB), giving two well-resolved emission colors. The aptamer binds to each dye with submicromolar K D values, and the resulting fluoromodules exhibit fluorescence … WebFeb 1, 2024 · Tailor-made probes having quadruplex inducing/stabilizing attachments of well-known dye molecules and its derivatives such as, coumarins, cyanines, thiazole orange, pyrazines, thioflavin T, triphenylmethane, tetraphenylethene, dimethylindole red etc have been employed.
Dimethylindole red
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WebTo develop novel label-free light-up probes with improved performance characteristics and low background, we selected DNA aptamers for dimethylindole red (DIR) by a modified affinity chromatography based SELEX method. DIR is an anionic propylsulfonate substituted red-emitting dye derivative of thiazole orange and exhibited weak fluorescence in fluid … Webderivatives, as well as dimethylindole red (DIR), oxazole-thiazole-blue (OTB), and various derivatives of these dyes, resulting in a range of fluoromodules with excitation/emission properties at any desired laser wavelength and emission range, typically with affinities for fluorogens in the low nanomolar to
WebAjit Sadana, in Engineering Biosensors, 2002. 10.1. INTRODUCTION. DNA–RNA hybridization wherein there is base pairing of a single-strand nucleic acid probe to a second complementary sequence contained in a second immobilized DNA or RNA target has recently gained increasing importance due to its applications in gene identification, …
WebSep 15, 2024 · The visible red band appeared on the T line after adding EC onto the sample pad for 1 min, and the color gradually deepened as time was extended. ... Selection and characterization of dimethylindole red DNA aptamers for the development of light-up fluorescent probes. Talanta, 168 (2024), pp. 217-221. View PDF View article Google … WebJun 1, 2024 · DIR is an anionic propylsulfonate substituted red-emitting dye derivative of thiazole orange and exhibited weak fluorescence in fluid solution and in the presence of …
WebPreviously, we determined that the yeast surface clone, V H -V L M8, could bind and activate the fluorogen dimethylindole red (DIR) but that the fluorogen activation …
WebA cyanine dye-dimethylindole red containing an extending polymethine chain, a sterically bulky dimethylindole heterocycle and an anionic propylsulfonate substituent on the quinoline ring was... proman sitio webWebMar 18, 2024 · DIR is an anionic propylsulfonate substituted red-emitting dye derivative of thiazole orange and exhibited weak fluorescence in fluid solution and in the presence of … proman software gmbhWebThe DIR2s RNA aptamer, a second-generation, in-vitro selected binder to dimethylindole red (DIR), activates the fluorescence of cyanine dyes, DIR and oxazole thiazole blue (OTB), allowing... proman sportsWebJul 17, 2024 · DNA-DNA reactions can be monitored with a label-free fluorogenic reaction. Guanosine-rich, single-stranded DNA oligonucleotides bind to thioflavin-T (ThT) and enhance the fluorescence of the dye. We discovered a novel DNA sequence that produces fluorescence upon binding to ThT. We denote this oligonucleotide ThTSignal. labetalol bcs classWebMar 18, 2011 · The U.S. Department of Energy's Office of Scientific and Technical Information proman staffing dickson tnWebA cyanine dye-dimethylindole red containing an extending polymethine chain, a sterically bulky dimethylindole heterocycle and an anionic propylsulfonate substituent on the quinoline ring was found to behave as a high specific light-up G-quadruplex probe in the red-emitting region above 650 nm, especially for parallel G-quadruplex c-myc. labetalol beyond use dateWeb2,3-Dimethylindole ≥97% Synonym (s): NSC 24936 Empirical Formula (Hill Notation): C10H11N CAS Number: 91-55-4 Molecular Weight: 145.20 EC Number: 202-076-2 MDL number: MFCD00005617 PubChem Substance ID: 24847431 Pricing and availability is not currently available. Properties Quality Level 100 assay ≥97% form solid bp 285 °C (lit.) mp proman staffing duncan sc