Cisplatin pulmonary hypertension
WebThe anticancer drug cisplatin induces cell death by apoptosis. Apoptosis is dependent on cellular loss of potassium ions (K+). We have recently shown that the antifungal drug amphotericin B (enhancin WebApr 11, 2024 · In cells and tissues, H 2 S is synthesized primarily from cysteine via cystathionine γ-lyase (CSE), cystathionine β synthetase (CBS), or 3-mercaptopyruvate sulfurtransferase (3-MST) in the transsulfuration pathway.
Cisplatin pulmonary hypertension
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Webities, hypertension, and proteinuria (Table 1). AGENTS WITH PREDOMONANLTY TUBULAR TOXICITY Platinum compounds Cisplatin(cis-dichlorodiammineplatinum)–platinum coordination complex is an effective chemotherapy against a wide spectrum of tumors such as testicular, head and neck, ovarian, lung, … WebNov 26, 2024 · Cisplatin is one of the commonly used anticancer drugs in clinic chemotherapy, but drug resistance is a major therapeutic obstacle for successful treatment. ... Idiopathic pulmonary fibrosis (IPF) ... Hypertension is a major healthcare problem globally. It often leads to cardiovascular disease complications, including myocardial …
WebAlthough cisplatin (cisPt) is one of the most often used cytotoxic drugs in the treatment of cancer, its clinical application is associated with nephrotoxicity 掌桥科研 一站式科研服务平台 Websone, high-dose cytarabine, and cisplatin (R-DHAP) chemotherapy was adminis-tered, along with filgrastim. ... management of pulmonary arterial hypertension and chronic thromboembolic pulmonary ...
WebPubMed® comprises more than 35 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites. WebCisplatin is one of the first-generation platinum-based cell-cycle nonspecific antineoplastic agents with a wide range of anticancer activities. The major adverse events of cisplatin include nephrotoxicity, neurotoxicity, ototoxicity, and gastrointestinal toxicities (>50 mg/m 2 ).
WebJan 7, 2024 · Data on the following variables were recorded: age, sex, diagnosis, height, weight, mannitol treatment, cisplatin treatment (number of treatments and absolute dose), hypertension (current antihypertensive treatment), diabetes, use of acetylsalicylic acid, use of angiotensin-converting enzyme (ACE)-inhibitors, tobacco use, exposure to ...
WebDec 2, 2024 · Minor adverse effects were observed in 2 patients, 1 with Grade II gastrointestinal reaction, and the other with pulmonary infection. Conclusion: Docetaxel … curated and madeWebApr 13, 2024 · Medications that may be prescribed to treat pulmonary hypertension symptoms or complications include: Blood vessel dilators (vasodilators). This type of … easy deductive reasoning puzzles printableWebMay 1, 2014 · This study considers the safety and tolerability of increasing doses of CX-4945 in combination with gemcitabine plus cisplatin to determine the maximum tolerated … easy deduction puzzles printableWebFeb 1, 2015 · Pulmonary veno-occlusive disease (PVOD) is an uncommon form of pulmonary hypertension (PH) characterized by progressive obstruction of small … curated and created ntuWebJan 16, 2024 · The mean cumulative cisplatin dose was 322 mg/m 2 in the group that did not have any VTE events. Eighteen events in the cisplatin group were DVT, as opposed … curated another wordWebAug 26, 2024 · Guidelines, Pulmonary hypertension, Pulmonary arterial hypertension, Chronic thrombo-embolic pulmonary hypertension, Left heart disease, Congenital heart disease, Lung disease, Connective tissue disease, Endothelin receptor antagonists, Phosphodiesterase type 5 inhibitors, Soluble guanylate cyclase stimulators, Prostacyclin … curated angWebJan 23, 2024 · The usual symptom is progressive dyspnea. PVOD may be associated with interstitial abnormalities; pleural effusions are commonly seen, which is unusual in … easy deep fried breadstick recipe